Abstract: Dynamic flexible job shop scheduling (DFJSS) is an important combinatorial optimisation problem, requiring simultaneous decision-making for machine assignment and operation sequencing in ...

The findings may help explain why this group has such exceptional memory. By Dana G. Smith Many people’s brains deteriorate as they age, becoming riddled with malfunctioning proteins that result in ...

A new study has uncovered new genetic rules that determine how CD8 “killer” T cells choose between becoming long-lasting, protective immune cells or slipping into exhausted, dysfunctional states.

This figure shows primary T cells modified using two approaches. CAR receptors are introduced through targeted DNA insertion (top), while CRISPRoff mRNA and guide RNAs silence additional genes through ...

Arc Institute, Gladstone Institutes, and University of California, San Francisco, scientists have developed an epigenetic editing platform that enables safe modification of multiple genes in primary ...

Modern humans may indeed have wiped out Neanderthals – but not through war or murder alone. A new study suggests that when the two species interbred, a slow-acting genetic incompatibility increased ...

Want a bespoke baby? Check the beauty, brains, or brawn boxes on the embryo order form. Genetic tinkering is no longer science fiction — it’s a market without legal guidelines or societal buy-in. But ...

If you’ve ever wondered why some people can eat whatever they want and stay slim while others struggle with weight despite their best efforts, genetics holds many of the answers. For people with ...

Proteogenomics explores how genetic information translates into protein expression and function, and the role of changes across DNA, RNA, and proteins in influencing disease development and ...

Collaborative research defines a novel approach to understanding how certain proteins called transcription factors determine which genetic programs will drive cell growth and maturation. The method, ...