Stuart Orkin and Swee Lay Thein shared a Breakthrough Prize in Life Sciences for their research on genetic causes of sickle ...

Sickle cell disease (SCD) is a group of genetic blood disorders. A person inherits SCD from their parents when they inherit two copies of the sickle cell gene, one from each parent. This hereditary ...

Sickle cell thalassemia occurs when you inherit both a sickle cell gene mutation and a thalassemia gene mutation. Symptoms are similar to other types of sickle cell disease but can vary depending on ...

September Is Sickle Cell Awareness Month. While many people are familiar with sickle cell anemia, sickle cell traits have also plagued our community. Sickle cell trait (SCT) is an inherited blood ...

Share on Pinterest World-first genetic therapy approved in the U.K. may be a game changer in sickle cell disease treatment. Image credit: Louise Morgan/Getty Images. As of 2021, almost 8 million ...

Exagamglogene autotemcel (exa-cel) is a nonviral cell therapy designed to reactivate fetal hemoglobin synthesis by means of ex vivo clustered regularly interspaced short palindromic repeats ...

This article is part of “Innovations In: Sickle Cell Disease,” an editorially independent special report that was produced with financial support from Vertex Pharmaceuticals. Nathan Wood is 15, lanky ...

This story is republished from STAT, the health and medicine news site that’s a partner to the Globe. Sign up for STAT’s free Morning Rounds newsletter here. Vertex executives warned that Casgevy, its ...

Gabriella Ngang, 18, of Farmington Hills is one of just three people in Michigan to take part in a clinical trial testing a new gene-editing therapy with the potential to cure her sickle cell disease.

Dr. Ya Haddy Sallah (Medicine): A 29-year-old man with sickle cell disease was admitted to this hospital because of pain in the right hip. The patient had received a diagnosis of sickle cell disease ...